(1S)-1-(4-chloro-3-methyl-phenyl)ethanamine ((1S)-1-(4-chloro-3-methyl-phenyl)ethanamine) is an organic compound. Its chemical formula is C10H14ClN, and its appearance is colorless to light yellow liquid or crystal. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Colorless to light yellow liquid or crystal
-Molecular weight: 187.68g/mol
-Melting point: 60-64 ℃
-Boiling point: 90-95 ℃
-Density: 1.049g/cm³
-Solubility: Soluble in organic solvents, slightly soluble in water
Use:
-In organic synthesis, this compound can be used as a precursor or intermediate to prepare other compounds.
-In the field of medicine, it is also used in the synthesis of certain drugs.
Method:
(1S)-1-(4-chloroo-3-methyl-phenyl) ethanamine can be prepared by the following steps:
1. 4-chloro-3-methylbenzaldehyde reacts with sodium bisulfite and methanol at room temperature to generate 4-chloro-3-methylbenzyl alcohol.
2. 4-chloro-3-methylbenzyl alcohol and o-methylaniline are heated to react in the presence of sulfuric acid to generate (1S)-1-(4-chloroo-3-methyl-phenyl) ethanamine.
Safety Information:
-The compound should be handled with caution and avoid contact with skin and eyes.
-Wear protective gloves, goggles and protective clothing during operation.
-Avoid inhaling gases, dust or haze from the compound.
-If necessary, operate in a well-ventilated place.
-Store it in a sealed container, away from fire and oxidizing agents.
-In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice.
-For detailed safety information on this compound, please refer to the relevant safety data sheet.